Basic Information
VIS ID
TVIS30011066
Fusion event
HIV-TAF2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
120798667/119786427 (Hg38)
End
120798667/119786427 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
TAF2
miRNAs that regulate target gene
hsa-mir-181a-5p ; hsa-mir-4803 ; hsa-mir-6739-3p ; hsa-mir-375 ; hsa-mir-6844 ; hsa-mir-6853-3p ; hsa-mir-1206 ; hsa-mir-3148 ; hsa-mir-651-3p
Nearest miRNA
hsa-mir-12123/Upstream/461162; hsa-mir-10400/Downstream/3429361;
Nearest TSS
ENST00000518652/Upstream/19299; ENST00000518057/Downstream/5447;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/369489, chr8-CpG: 29/Downstream/46131
Upstream sequence
TTCAGTTCTTTCCCTTCAATCACCATTTTTCTAATATTTCCTCTAGGTATTAATCCAACAAGACTAACAAGAATGAACCTATTTGTCTTGAATTTTTTTC
Downstream sequence
TAGTACCAAAAACTAAAACTTTCATTCTAGCTCCTCGGCCTCTACCTTCAAACAAAATGAGGATTCTTAAAACTAAATGTTAAAAATTCTTATAAAAATG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate