Basic Information
VIS ID
TVIS30011067
Fusion event
HIV-MRPL13 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
121421780/120409541 (Hg38)
End
121421780/120409541 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
MRPL13
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-20a-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-12123/Upstream/1084276; hsa-mir-10400/Downstream/2806247;
Nearest TSS
ENST00000518652/Upstream/64095; ENST00000456899/Downstream/4571;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/284002, chr8-CpG: 24/Downstream/35572
Upstream sequence
GTGTTGGCAAAACTGCAATAATCATGTAACAATTGATAGTATTAAAATAAATTGACCATTTTAAAGCTACAATCTTAAGCAACAGAATTGTGAAGAAAAG
Downstream sequence
ATAGTGCTATTTTTTTCCTTTAAAGAAAAAAGAAAAAAAATCTAAGTATAAACCCCACAGTCACCATTTGCACATTGCAAATACATATCTGCTTTGTACA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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