Basic Information
VIS ID
TVIS30011068
Fusion event
HIV-TBC1D31 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
124128229/123115989 (Hg38)
End
124128229/123115989 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
TBC1D31
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-615-3p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-12123/Upstream/3790724; hsa-mir-10400/Downstream/99799;
Nearest TSS
ENST00000518652/Upstream/6655; ENST00000518866/Downstream/11861;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/42911, chr8-CpG: 31/Downstream/40810
Upstream sequence
tgcaaaatctcatgtaaaataatatcttcatggattacagggattagagcatggacatcttttggggagggggacagttttcattattctgcttgccaca
Downstream sequence
TTAACTATAAAGTATACTCAGAAAAATAATTTATATTTAAACAGTAATGAAAGGGAATTAGCCTTAAAAATATTAAAAGCTATTATAAAGCATTGAAATT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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