Basic Information
VIS ID
TVIS30011086
Fusion event
HIV-CNTLN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
17462668/17462670 (Hg38)
End
17462668/17462670 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9G
Target gene
CNTLN
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-10a-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-222-5p ; hsa-mir-545-5p ; hsa-mir-548m ; hsa-mir-329-5p ; hsa-mir-15b-3p ; hsa-mir-3122 ; hsa-mir-3913-5p ; hsa-mir-450a-1-3p ; hsa-mir-6513-5p ; hsa-mir-6716-5p ; hsa-mir-887-5p ; hsa-mir-3672 ; hsa-mir-6818-3p ; hsa-mir-6864-3p
Nearest miRNA
hsa-mir-101-2/Upstream/11454766; hsa-let-7a-1/Downstream/1110636;
Nearest TSS
ENST00000422679/Upstream/46852; ENST00000467085/Downstream/116412;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/326962, chr9-CpG: 120/Downstream/116053
Upstream sequence
TGTTTTAAGTGATCTTCTTAAATCATTAAAATTCTTAATTATTCACATATTTACATTATACCAGGACAACTCATATTTCCTGTAAATGTATTTTGGATAC
Downstream sequence
ATACTCTTTGCAATTCTTAAATGATTGTGTTCCTCTATAGTTTGGCATGTTATATAAAAGTTTTAGTATTATTATTTCTATTACAGCATATAAAATAAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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