Basic Information
VIS ID
TVIS30011177
Fusion event
HIV-EIF4G3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
21212784/20886291 (Hg38)
End
21212784/20886291 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA1A
Target gene
EIF4G3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-221-3p ; hsa-mir-17-5p ; hsa-mir-3613-3p ; hsa-mir-543 ; hsa-mir-136-5p ; hsa-mir-377-5p ; hsa-mir-218-5p ; hsa-mir-548c-3p ; hsa-mir-4724-3p ; hsa-mir-6813-3p ; hsa-mir-3200-3p
Nearest miRNA
hsa-mir-12136/Upstream/252503; hsa-mir-101-1/Downstream/102023;
Nearest TSS
ENST00000473358/Upstream/38346; ENST00000416959/Downstream/55107;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/98663, chr1-CpG: 77/Downstream/290331
Upstream sequence
TGTTCTCACCTGGGTTTTAATGTTTTCGGGATCATCGGCTTGGCTGTCTCGTTTTTGGCTTGGCTTCCAGGCATTTTCTGCCTTTTTCAGGTGTACATCT
Downstream sequence
TCTTTTACAGAAACTGTGATGATCTTTCTGGGTTCTCTTCTTTGGCCAGGTTGAGATCTTCGTGACCCAACATTCAACAACTAGGACAAGAATATTACAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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