Basic Information
VIS ID
TVIS30011191
Fusion event
HIV-MACO1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
25762688/25436197 (Hg38)
End
25762688/25436197 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
MACO1
miRNAs that regulate target gene
hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6832-3p ; hsa-mir-627-3p
Nearest miRNA
hsa-mir-12136/Upstream/412611; hsa-mir-101-1/Downstream/470165;
Nearest TSS
ENST00000473358/Upstream/5277; ENST00000470035/Downstream/12696;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4573, chr1-CpG: 109/Downstream/107205
Upstream sequence
GGCCTCTCTTGAACCTCACTAGATTTAGAGATTGATCTTAATGGTAGGTTTAACAAATAATTATTTACATTTTCTTACTAGTTATATGCTTGTATATATC
Downstream sequence
TCATGGACCCAGTCCATGTTCTGTAAGCATTTATGTTCCTAGAATCTTTTTCTTTGGCCATTTCTCCCAGATCTCCCCACTGATACTGTTAACCCTTTGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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