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Viral Integration Site DataBase
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TVIS30011298
Basic Information
VIS ID
TVIS30011298
Fusion event
HIV-NOTCH2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
120564906/120022283 (Hg38)
End
120564906/120022283 (Hg38)
Orient
+
Location type
Intronic
Target gene
NOTCH2
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-16-5p
;
hsa-mir-181c-5p
;
hsa-mir-326
;
hsa-mir-34a-5p
;
hsa-mir-107
;
hsa-mir-155-5p
;
hsa-mir-183-5p
;
hsa-mir-181a-5p
;
hsa-mir-744-5p
;
hsa-mir-130b-5p
;
hsa-mir-27b-3p
;
hsa-mir-196a-5p
;
hsa-mir-106a-5p
;
hsa-mir-92a-3p
;
hsa-mir-25-3p
;
hsa-mir-17-5p
;
hsa-let-7c-5p
;
hsa-mir-29b-3p
;
hsa-mir-6868-3p
;
hsa-mir-182-5p
;
hsa-mir-3124-3p
;
hsa-mir-515-5p
;
hsa-mir-519e-5p
;
hsa-mir-3942-3p
;
hsa-mir-23b-3p
;
hsa-mir-205-5p
;
hsa-mir-96-5p
;
hsa-mir-1271-5p
;
hsa-mir-5695
;
hsa-mir-519d-5p
;
hsa-mir-6838-5p
;
hsa-mir-4274
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-29b-1-5p
;
hsa-mir-543
;
hsa-mir-4753-3p
;
hsa-mir-5100
;
hsa-mir-6794-3p
;
hsa-mir-210-5p
;
hsa-mir-4749-3p
;
hsa-mir-1248
;
hsa-mir-1237-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-10b-3p
;
hsa-mir-4639-3p
;
hsa-mir-146a-5p
;
hsa-mir-9-3p
;
hsa-mir-9-5p
;
hsa-mir-191-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2927555; hsa-mir-1182/Downstream/25828304;
Nearest TSS
ENST00000473358/Upstream/35233;
ENST00000608123/Downstream/7680;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/125686
,
chr1-CpG: 95/Downstream/46451
Nearest cancer related gene
NOTCH2
(TSG, No orient, 0)
Upstream sequence
TCATATTTGATAAAGGATTTTAATAGGACATAAGTATTAATAAGAATCACTTAGGAATGGTACTGTTAAAGGGTCCAGATCTCAAGTCCTAATACAAGGA
Downstream sequence
AAAGCCTCACAGGACATACTCATATGCATCTGTAACTCACTATGCAAATGTAAGGTGCCATATTCAACAACTTGTGACTTTTGTGCTGGCAACAACATTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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