Basic Information
VIS ID
TVIS30011305
Fusion event
HIV-BCL9 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
147057991/147586189 (Hg38)
End
147057991/147586189 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
BCL9
miRNAs that regulate target gene
hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-mir-605-5p ; hsa-mir-92a-3p ; hsa-mir-30c-2-3p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1735544; hsa-mir-1182/Downstream/748290;
Nearest TSS
ENST00000473358/Upstream/44777; ENST00000497938/Downstream/14007;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/342561, chr1-CpG: 81/Downstream/13267
Nearest cancer related gene
BCL9(OG, No orient, 0)
Upstream sequence
CAACTGATCACCTTCCTAAACTCACCTTATTAACTCTGCTTTTCTTTTAAAAGCTCTGCCGTTTTCCCCACAGCCCAGCTTAGCTccctaaagtcatgtg
Downstream sequence
tgactcagcctttccacccacttcagttgcccagggagccatgtagattctgccacccaaatgtcttacatctgtcccttccctattcttccccctccca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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