Basic Information
VIS ID
TVIS30011308
Fusion event
HIV-HIST2H2BE integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
149856893/149885343 (Hg38)
End
149856893/149885343 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA1F
Target gene
HIST2H2BE
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-296-3p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-mir-760 ; hsa-mir-6822-3p ; hsa-mir-6792-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-5693 ; hsa-mir-8057 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6802-5p ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-4766-5p ; hsa-mir-146a-3p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-1276
Nearest miRNA
hsa-mir-101-1/Upstream/1496980; hsa-mir-1182/Downstream/607002;
Nearest TSS
ENST00000473358/Upstream/24072; ENST00000331380/Downstream/1309;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/23658, chr1-CpG: 133/Downstream/876
Upstream sequence
CAACAATATTAGATCAATACGTAGTATTTAAGTGTCCATAATGTGCCAGGCTGAAGATGCACGGGAAAACCACACTAGCCGGTCTGTCAAGGGCTTGAGA
Downstream sequence
ATACCATAAACAAGAAAACAGACGAACCAATTTCAGACAGCTGCTAGAAGGAAGATAAAATGAGACAGGCAAGTATGAGAGGCGCGAATTCCTGAGTGGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate