Basic Information
VIS ID
TVIS30011312
Fusion event
HIV-VPS45 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
150116721/150144543 (Hg38)
End
150116721/150144543 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
VPS45
miRNAs that regulate target gene
hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-34a-5p ; hsa-mir-186-5p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-186-3p ; hsa-mir-6782-3p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a
Nearest miRNA
hsa-mir-101-1/Upstream/1756180; hsa-mir-1182/Downstream/347802;
Nearest TSS
ENST00000473358/Upstream/35368; ENST00000492304/Downstream/4640;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/76785, chr1-CpG: 190/Downstream/4962
Upstream sequence
TGAAATGTTAGTCTTAATAGATCTTACAAATTTAATTCTAAAAAAAAAAATGAAGACCCTGGGGAAGAGCACAGAAGGACTGTCCTTGCAGTATGGATGT
Downstream sequence
TGTAGTGCTCAACTGATGCTTCCATTCTATACCCAAATATCAGACCAGTACCTCCTGCCTACTATTCATGATATATTTTCATCTGGTTAGATGTCCAGAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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