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Viral Integration Site DataBase
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TVIS30011314
Basic Information
VIS ID
TVIS30011314
Fusion event
HIV-MCL1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
150547187/150574711 (Hg38)
End
150547187/150574711 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA1F
Target gene
MCL1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-15a-5p
;
hsa-mir-193a-3p
;
hsa-mir-133b
;
hsa-mir-29a-3p
;
hsa-mir-29b-3p
;
hsa-mir-29c-3p
;
hsa-mir-101-3p
;
hsa-mir-153-3p
;
hsa-mir-512-5p
;
hsa-mir-320a
;
hsa-mir-193b-3p
;
hsa-mir-518a-5p
;
hsa-mir-582-5p
;
hsa-mir-661
;
hsa-mir-876-3p
;
hsa-mir-892b
;
hsa-mir-148b-5p
;
hsa-mir-886-3p
;
hsa-mir-125b-5p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-151a-3p
;
hsa-mir-186-5p
;
hsa-mir-26b-5p
;
hsa-mir-615-3p
;
hsa-mir-30d-5p
;
hsa-mir-133a-3p
;
hsa-mir-26a-5p
;
hsa-mir-3679-3p
;
hsa-mir-139-5p
;
hsa-mir-761
;
hsa-mir-20a-5p
;
hsa-mir-7153-3p
;
hsa-mir-596
;
hsa-mir-4293
;
hsa-mir-6747-3p
;
hsa-mir-4773
;
hsa-mir-7159-3p
;
hsa-mir-495-3p
;
hsa-mir-5688
;
hsa-mir-106b-5p
;
hsa-mir-1264
;
hsa-mir-3184-3p
;
hsa-mir-8080
;
hsa-mir-4452
;
hsa-mir-1469
;
hsa-mir-545-5p
;
hsa-mir-144-3p
;
hsa-mir-200a-3p
;
hsa-mir-141-3p
;
hsa-mir-7702
;
hsa-mir-5682
;
hsa-mir-767-5p
;
hsa-mir-6871-3p
;
hsa-mir-6836-3p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-6778-3p
;
hsa-mir-6771-3p
;
hsa-mir-660-3p
;
hsa-mir-6749-3p
;
hsa-mir-5193
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-93-5p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-17-5p
;
hsa-mir-125a-5p
;
hsa-mir-302b-3p
;
hsa-mir-34a-5p
;
hsa-mir-339-3p
;
hsa-mir-30c-5p
;
hsa-mir-1207-5p
;
hsa-mir-1909-3p
;
hsa-mir-211-3p
;
hsa-mir-3127-5p
;
hsa-mir-3153
;
hsa-mir-320b
;
hsa-mir-320c
;
hsa-mir-320d
;
hsa-mir-4270
;
hsa-mir-4429
;
hsa-mir-4441
;
hsa-mir-4736
;
hsa-mir-4763-3p
;
hsa-mir-5000-5p
;
hsa-mir-6508-5p
;
hsa-mir-6722-3p
;
hsa-mir-6733-5p
;
hsa-mir-6739-5p
;
hsa-mir-6754-5p
;
hsa-mir-6757-5p
;
hsa-mir-6783-5p
;
hsa-mir-7150
;
hsa-mir-8065
;
hsa-mir-8067
Nearest miRNA
hsa-mir-101-1/Upstream/22697; hsa-mir-1182/Downstream/971085;
Nearest TSS
ENST00000473358/Upstream/16457;
ENST00000636087/Downstream/4066;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/12886
,
chr1-CpG: 103/Downstream/4141
Nearest cancer related gene
MCL1
(OG, No orient, 0)
Upstream sequence
ACACTACATTTGACAACCAACATTAATTTGTAGTTGGTCCTAACCCTTCCTGGCACAGCTATCAAAAGTACAGCTGTTTAACCAGAACCAAGGTGTTCAC
Downstream sequence
CCCCCACAGAATGTACATGAAACACTAGAGGACTGCATGTTTTTCCCTGAGAGAAGCGTAAGACAAACAGAAGTCAAAAAGTAGTCACTGGGAGCGCCAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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