Basic Information
VIS ID
TVIS30011350
Fusion event
HIV-COP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
175945157/175976021 (Hg38)
End
175945157/175976021 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1G
Target gene
COP1
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-1180-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/7542; hsa-mir-1182/Downstream/1053342;
Nearest TSS
ENST00000473358/Upstream/28695; ENST00000426030/Downstream/41256;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/376349, chr1-CpG: 108/Downstream/230554
Nearest cancer related gene
COP1(TSG, No orient, 0)
Upstream sequence
CTACCAGTAAGAACAGTGAGATCTCCATAAGGGATCTTAGAATTTGTTTTGCTATCAATGACATTTCATGCTTTCTATTAGTAAAGGGAAAATCAGTTGT
Downstream sequence
CAGATCTCAAAAATCCAGTAATATGTAAAAGATGTAGAATTAGAAGGTCTCAAAGGTCTCAATCCTTTACAAAACAAAAAACTTTGAGAAAATAAGAATA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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