Basic Information
VIS ID
TVIS30011364
Fusion event
HIV-PTPRC integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
198634771/198665642 (Hg38)
End
198634771/198665642 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
PTPRC
miRNAs that regulate target gene
hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4653-3p ; hsa-mir-4748 ; hsa-mir-4464
Nearest miRNA
hsa-mir-101-1/Upstream/2083161; hsa-mir-1182/Downstream/193231;
Nearest TSS
ENST00000473358/Upstream/26354; ENST00000484135/Downstream/1419;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/506408, chr1-CpG: 36/Downstream/1369704
Nearest cancer related gene
PTPRC(TSG, No orient, 0)
Upstream sequence
CAGGTCCCCGTGGTTGTCTGACCCAGACTTCCACCTTGAGGTAACTGGGGTAACTATAACGATATTTTCATCCTGATCTCTTCATGCAGTTATATGTTTC
Downstream sequence
CAAGAACAGATAAACTGTGAACTTAATACAAGTGTCTCCTTTCCTTGGATTCTCACCATCTGGGTGGTAAACATGACAGAAACATTCAAGTATGTTCAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate