Basic Information
VIS ID
TVIS30011446
Fusion event
HIV-PPP3CB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
75212832/73453074 (Hg38)
End
75212832/73453074 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP3CB
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-6818-5p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-1178-3p ; hsa-mir-6509-3p ; hsa-mir-5093 ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-5699-5p ; hsa-mir-875-3p ; hsa-mir-1273g-3p ; hsa-mir-6769a-3p ; hsa-mir-181a-2-3p
Nearest miRNA
hsa-mir-1265/Upstream/731974; hsa-mir-107/Downstream/2099384;
Nearest TSS
ENST00000439456/Upstream/19513; ENST00000595595/Downstream/14545;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/38882, chr10-CpG: 45/Downstream/42201
Upstream sequence
CGAAAAGTGATCAAATGAAATGGATAGTTTACACAGTTGGAAAAACAGTAATTTTCTTCttagcatcattagaaatcaaagaaatgtaaacttaagcaac
Downstream sequence
tataatttactactatatagccatgaagaaaataagtaaaaatgaccaaaatccaatgaggtagtcctgtggagaaatatgtttatggattccttgctgg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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