Basic Information
VIS ID
TVIS30011454
Fusion event
HIV-WAPL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
88205601/86445844 (Hg38)
End
88205601/86445844 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
WAPL
miRNAs that regulate target gene
hsa-mir-148a-3p ; hsa-mir-193b-3p ; hsa-mir-20a-3p ; hsa-mir-1306-5p ; hsa-mir-8063 ; hsa-mir-3675-3p ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-2355-5p ; hsa-mir-3941 ; hsa-mir-6793-3p ; hsa-mir-323b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-362-3p
Nearest miRNA
hsa-mir-1265/Upstream/181056; hsa-mir-107/Downstream/1058037;
Nearest TSS
ENST00000439456/Upstream/1812; ENST00000428940/Downstream/21662;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/43984, chr10-CpG: 137/Downstream/75034
Nearest cancer related gene
WAPL(OG, No orient, 0)
Upstream sequence
ctagcctcaagtaatcctcctgcttcagcctcccaaagtgctgggctcacaggtgtgagccaccAGCCTACAGTATATTTCTTACTGTGTTTACCATCTA
Downstream sequence
GTACTTACACTTTGAGAACTATTACTGTAATCTGACAATAGATCTTCAAGTTTAAAGTGAAGCTGAAAAAACAATCTCAAAAACTGAAAACTGAAAAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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