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TVIS30011457
Basic Information
VIS ID
TVIS30011457
Fusion event
HIV-PTEN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
GRCh37/hg19
Start
89689448/87929691 (Hg38)
End
89689448/87929691 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
PTEN
miRNAs that regulate target gene
hsa-mir-17-5p
;
hsa-mir-217
;
hsa-mir-216a-5p
;
hsa-mir-214-3p
;
hsa-mir-26a-5p
;
hsa-mir-21-5p
;
hsa-mir-494-3p
;
hsa-mir-19a-3p
;
hsa-mir-141-3p
;
hsa-mir-20a-5p
;
hsa-mir-18a-5p
;
hsa-mir-19b-3p
;
hsa-mir-221-3p
;
hsa-mir-222-3p
;
hsa-mir-106b-5p
;
hsa-mir-29b-3p
;
hsa-mir-519d-3p
;
hsa-mir-93-5p
;
hsa-mir-519a-3p
;
hsa-mir-519c-3p
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-22-3p
;
hsa-mir-25-3p
;
hsa-mir-23a-3p
;
hsa-mir-29a-3p
;
hsa-mir-23b-3p
;
hsa-mir-144-3p
;
hsa-mir-106a-5p
;
hsa-mir-193b-3p
;
hsa-mir-181b-5p
;
hsa-mir-182-5p
;
hsa-mir-128-3p
;
hsa-mir-29c-3p
;
hsa-mir-425-5p
;
hsa-mir-382-5p
;
hsa-mir-92a-1-5p
;
hsa-mir-92a-3p
;
hsa-mir-32-5p
;
hsa-mir-200a-3p
;
hsa-mir-130b-3p
;
hsa-mir-301a-3p
;
hsa-mir-492
;
hsa-mir-20b-5p
;
hsa-mir-10b-5p
;
hsa-mir-155-3p
;
hsa-mir-205-5p
;
hsa-mir-429
;
hsa-mir-718
;
hsa-mir-10a-5p
;
hsa-mir-92b-3p
;
hsa-mir-153-3p
;
hsa-mir-26b-5p
;
hsa-mir-320a
;
hsa-mir-543
;
hsa-mir-376a-5p
;
hsa-mir-7856-5p
;
hsa-mir-4653-3p
;
hsa-mir-4328
;
hsa-mir-34a-3p
;
hsa-mir-607
;
hsa-mir-3658
;
hsa-mir-6842-3p
;
hsa-mir-3144-3p
;
hsa-mir-3671
;
hsa-mir-3653-3p
;
hsa-mir-5787
;
hsa-mir-4505
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-4791
;
hsa-mir-3201
;
hsa-mir-1287-5p
;
hsa-mir-7853-5p
;
hsa-mir-105-5p
;
hsa-mir-4272
;
hsa-mir-889-5p
;
hsa-mir-6074
;
hsa-mir-6512-5p
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-216b-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-548av-3p
;
hsa-mir-26a-2-3p
;
hsa-mir-26a-1-3p
;
hsa-mir-652-5p
;
hsa-mir-548as-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-377-3p
;
hsa-mir-6826-5p
;
hsa-mir-301b-3p
;
hsa-mir-130a-3p
;
hsa-mir-181a-5p
;
hsa-mir-29a-5p
;
hsa-mir-142-5p
;
hsa-mir-106a-3p
;
hsa-mir-106b-3p
;
hsa-mir-17-3p
;
hsa-mir-20a-3p
;
hsa-mir-193a-3p
;
hsa-mir-190b
;
hsa-mir-370-5p
;
hsa-mir-302a-3p
;
hsa-mir-301a-5p
;
hsa-mir-200a-5p
;
hsa-mir-130a-5p
;
hsa-mir-181c-5p
;
hsa-mir-200c-3p
;
hsa-mir-518c-3p
;
hsa-mir-638
;
hsa-mir-200c-5p
;
hsa-mir-486-5p
;
hsa-mir-494-5p
;
hsa-mir-744-3p
;
hsa-mir-1273g-3p
;
hsa-mir-1250-3p
;
hsa-mir-155-5p
;
hsa-mir-21-3p
;
hsa-mir-152-3p
Nearest miRNA
hsa-mir-1265/Upstream/425737; hsa-mir-107/Downstream/1133644;
Nearest TSS
ENST00000439456/Upstream/4168;
ENST00000472832/Downstream/22508;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/65363
,
chr10-CpG: 61/Downstream/653080
Nearest cancer related gene
PTEN
(TSG, No orient, 0)
Upstream sequence
ATATATGTGCATATGTCATTACTAAATGCATTTTCTTTCTAGAAAAACTCAATATACTAAATTGTACTAAAAAGGAAAAGCTTGTTTTGTTTTGAGTGGT
Downstream sequence
AGTATGAAAGTTGTTTTATTTTAGGTCTGACCAGTTAGAAACCAATGGATTGTAGTTTATTTATAATTAGTTAAACCTTCATGTGAATTTGGTTTTGAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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