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Viral Integration Site DataBase
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TVIS30011573
Basic Information
VIS ID
TVIS30011573
Fusion event
HIV-PACS1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
65890430/66122959 (Hg38)
End
65890430/66122959 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
PACS1
miRNAs that regulate target gene
hsa-mir-324-5p
;
hsa-mir-320a
;
hsa-mir-218-5p
;
hsa-mir-6869-5p
;
hsa-mir-526b-5p
;
hsa-mir-431-5p
;
hsa-mir-4711-5p
;
hsa-mir-935
;
hsa-mir-3662
;
hsa-mir-6513-5p
;
hsa-mir-599
;
hsa-mir-5089-5p
;
hsa-mir-6728-5p
;
hsa-mir-769-3p
;
hsa-mir-450b-3p
;
hsa-mir-3145-3p
;
hsa-mir-610
;
hsa-mir-3614-5p
;
hsa-mir-4461
;
hsa-mir-6079
;
hsa-mir-6077
;
hsa-mir-7-5p
;
hsa-mir-9-5p
;
hsa-mir-8485
;
hsa-mir-1200
;
hsa-mir-4284
;
hsa-mir-4772-3p
;
hsa-mir-4682
;
hsa-mir-3653-5p
;
hsa-mir-1304-3p
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-660-3p
;
hsa-mir-6890-3p
;
hsa-mir-1306-5p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-6741-3p
;
hsa-mir-2861
;
hsa-mir-3134
;
hsa-mir-449b-3p
;
hsa-mir-4534
;
hsa-mir-602
;
hsa-mir-6081
;
hsa-mir-6749-5p
;
hsa-mir-8082
Nearest miRNA
hsa-mir-10392/Upstream/473706; hsa-let-7a-2/Downstream/811475;
Nearest TSS
ENST00000527297/Upstream/22196;
ENST00000531298/Downstream/93239;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/51781
,
chr11-CpG: 120/Downstream/134480
Upstream sequence
ataatgtattacaataatttataacaataactatgtattacataaacttagtgataaagcagcagtaaggtttgagagaactgaatccaattttgcgaga
Downstream sequence
aattctgctgtgggtagcatgctatcaaatgtattgcatactttagagaaatctttaatgaaaggaagagtcagtgtgacaaacttcattgtcttatttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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