Basic Information
VIS ID
TVIS30011615
Fusion event
HIV-ACER3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.5
Reference genome
GRCh37/hg19
Start
76673573/76962529 (Hg38)
End
76673573/76962529 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
ACER3
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-340-5p ; hsa-mir-410-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-3163 ; hsa-mir-1277-5p ; hsa-mir-6507-5p ; hsa-mir-5692a ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-2681-5p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-580-3p ; hsa-mir-4724-3p ; hsa-mir-6782-3p ; hsa-mir-130b-5p ; hsa-mir-1250-3p ; hsa-mir-1301-3p ; hsa-mir-145-3p ; hsa-mir-153-5p ; hsa-mir-335-3p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-4660 ; hsa-mir-5047 ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-6516-5p ; hsa-mir-664b-3p ; hsa-mir-7156-3p
Nearest miRNA
hsa-mir-10392/Upstream/1627343; hsa-let-7a-2/Downstream/2439493;
Nearest TSS
ENST00000527297/Upstream/35972; ENST00000525325/Downstream/16090;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/101282, chr11-CpG: 134/Downstream/77119
Upstream sequence
ggctggtcttgaactcttgacctcagatgatccacccacctggcctcccaaagtgctgggaatacaggcgtgagccactgtgcctggccTGTCAAGTATT
Downstream sequence
TTTTaaaggtttattctgagccaatattagtgaccatggcATGGTGtgatactggtgggctgggggaagtccccaaacagcagtggacctctatcctagc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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