Basic Information
VIS ID
TVIS30011623
Fusion event
HIV-MAML2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q21
Reference genome
GRCh37/hg19
Start
95897348/96164184 (Hg38)
End
95897348/96164184 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAML2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-218-5p ; hsa-mir-6868-3p ; hsa-mir-6715b-3p ; hsa-mir-3605-3p ; hsa-mir-205-5p
Nearest miRNA
hsa-mir-10392/Upstream/1697604; hsa-let-7a-2/Downstream/177254;
Nearest TSS
ENST00000527297/Upstream/70664; ENST00000332349/Downstream/178996;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/239983, chr11-CpG: 75/Downstream/225188
Nearest cancer related gene
MAML2(OG, No orient, 0)
Upstream sequence
aagctggtctcgaactcctgacctcaagttatccacctgcctcagcttccaaaagtgctgtgattataggcatgagccaccgtgcccagccAATACTGCG
Downstream sequence
CTTTCACAAATCCAAGCTGCAGGAAACAGATGAAAGAGCATTATATTGCCTTCTGGTTATGGGTCAGTCTATCTCTGTGAATCTagtcataaaagcatag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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