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TVIS30011767
Basic Information
VIS ID
TVIS30011767
Fusion event
HIV-APAF1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
99085661/98691883 (Hg38)
End
99085661/98691883 (Hg38)
Orient
+
Location type
Intronic
Target gene
APAF1
miRNAs that regulate target gene
hsa-mir-21-5p
;
hsa-mir-335-5p
;
hsa-mir-155-5p
;
hsa-mir-624-3p
;
hsa-mir-221-3p
;
hsa-mir-23a-3p
;
hsa-mir-4294
;
hsa-mir-1273e
;
hsa-mir-6894-5p
;
hsa-mir-4722-5p
;
hsa-mir-1827
;
hsa-mir-7162-3p
;
hsa-mir-4649-3p
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-940
;
hsa-mir-6808-5p
;
hsa-mir-6893-5p
;
hsa-mir-4435
;
hsa-mir-2861
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-564
;
hsa-mir-4755-3p
;
hsa-mir-3179
;
hsa-mir-3190-5p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-6715b-5p
;
hsa-mir-4269
;
hsa-mir-3622a-5p
;
hsa-mir-216b-5p
;
hsa-mir-216a-5p
;
hsa-mir-6771-5p
;
hsa-mir-7977
;
hsa-mir-933
;
hsa-mir-7160-5p
;
hsa-mir-219b-3p
;
hsa-mir-20b-3p
;
hsa-mir-6746-5p
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-1228-3p
;
hsa-mir-2114-5p
;
hsa-mir-5588-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-302f
;
hsa-mir-26a-1-3p
;
hsa-mir-23a-5p
;
hsa-mir-34a-5p
Nearest miRNA
hsa-let-7i/Upstream/696435; hsa-mir-1178/Downstream/1498001;
Nearest TSS
ENST00000382841/Upstream/21022;
ENST00000546491/Downstream/7613;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/46178
,
chr12-CpG: 42/Downstream/53725
Nearest cancer related gene
APAF1
(TSG, No orient, 0)
Upstream sequence
TTAGCTCTCTGATCCCTTCATTAACTATTTTCCCTGACCATTAAAATGTAGCTATTCCTGCAGCATCTAACCTTGGCTACCACCTCTATCACCGCTCTTC
Downstream sequence
CATCCCAGTTCATTCAGTCTCATGGCTTCAACTCATCTTTTTTCAGGTATGTCATCTGCAACCTTCATTTTATGAGCTGTGTTCTTCATTCCTAACTTCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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