Basic Information
VIS ID
TVIS30011777
Fusion event
HIV-PHETA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
111802778/111364974 (Hg38)
End
111802778/111364974 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
PHETA1
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-1972 ; hsa-mir-214-3p ; hsa-mir-4267 ; hsa-mir-4269 ; hsa-mir-4514 ; hsa-mir-4692 ; hsa-mir-4755-3p ; hsa-mir-5582-5p ; hsa-mir-6715b-5p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-1207-3p ; hsa-mir-138-5p ; hsa-mir-2861 ; hsa-mir-3065-3p ; hsa-mir-3667-3p ; hsa-mir-383-3p ; hsa-mir-384 ; hsa-mir-4297 ; hsa-mir-4456 ; hsa-mir-4757-5p ; hsa-mir-5571-3p ; hsa-mir-5581-5p ; hsa-mir-5702 ; hsa-mir-6744-3p ; hsa-mir-6765-3p ; hsa-mir-6804-3p ; hsa-mir-6878-3p ; hsa-mir-7851-3p ; hsa-mir-7975 ; hsa-mir-937-5p ; hsa-mir-939-3p
Nearest miRNA
hsa-let-7i/Upstream/60765; hsa-mir-1178/Downstream/434860;
Nearest TSS
ENST00000382841/Upstream/1225; ENST00000548846/Downstream/4121;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1534, chr12-CpG: 50/Downstream/3781
Upstream sequence
ccgagattgcactactacactccagcctggggacagagccagactccgtctcaaaaaaaaagaaagaaTTTGGGGAAAGATGCAGGCCCAGGGCTAGGCT
Downstream sequence
GACTTACAGGAAGGAGGGGCAGGGGGTCGACCCGTGCCATTTAGCATAGAGGACTCTAACTCCATGCCATCGGCCACAGTGACCCCATCCACCTTCCCCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate