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Viral Integration Site DataBase
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TVIS30011791
Basic Information
VIS ID
TVIS30011791
Fusion event
HIV-KSR2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.22
Reference genome
GRCh37/hg19
Start
118094695/117656890 (Hg38)
End
118094695/117656890 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
;
FRA12C
Target gene
KSR2
miRNAs that regulate target gene
hsa-mir-940
;
hsa-mir-7847-3p
;
hsa-mir-6894-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-4751
;
hsa-mir-766-5p
;
hsa-mir-139-5p
;
hsa-mir-3922-5p
;
hsa-mir-5582-5p
;
hsa-mir-2113
;
hsa-mir-218-5p
;
hsa-mir-7106-3p
;
hsa-mir-361-3p
;
hsa-mir-6793-3p
;
hsa-mir-483-3p
;
hsa-mir-4700-3p
;
hsa-mir-642a-5p
;
hsa-mir-1236-3p
;
hsa-mir-4469
;
hsa-mir-6515-3p
;
hsa-mir-2276-5p
;
hsa-mir-5188
;
hsa-mir-1243
;
hsa-mir-3654
;
hsa-mir-6892-3p
;
hsa-mir-4732-5p
;
hsa-mir-6832-5p
;
hsa-mir-7107-3p
;
hsa-mir-6753-3p
;
hsa-mir-20b-3p
;
hsa-mir-3137
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
;
hsa-mir-6739-3p
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-607
;
hsa-mir-511-5p
;
hsa-mir-6888-3p
;
hsa-mir-6715b-3p
;
hsa-mir-6830-3p
;
hsa-mir-3120-5p
;
hsa-mir-4732-3p
;
hsa-mir-6732-3p
;
hsa-mir-6715a-3p
;
hsa-mir-1324
Nearest miRNA
hsa-let-7i/Upstream/1228572; hsa-mir-1178/Downstream/2056744;
Nearest TSS
ENST00000382841/Upstream/101661;
ENST00000544667/Downstream/20361;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/295247
,
chr12-CpG: 50/Downstream/104072
Nearest cancer related gene
KSR2
(OG, No orient, 0)
Upstream sequence
tattagactctaagttcttcagttctgggactcagactggctctccttgctcctcagcttgcagacagcctattgtaggaccttgtgatcatgtaagtta
Downstream sequence
atacttaataaactcccctttgtgtgtgtgtgtatacatatatataataggatatatatatatatataataggatatatatatataataggatatatata
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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