Basic Information
VIS ID
TVIS30011798
Fusion event
HIV-ANAPC5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
121755395/121317592 (Hg38)
End
121755395/121317592 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
ANAPC5
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-1227-3p ; hsa-mir-26b-3p ; hsa-mir-34a-5p ; hsa-mir-93-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-let-7i/Upstream/594326; hsa-mir-3612/Downstream/126681;
Nearest TSS
ENST00000382841/Upstream/7198; ENST00000557474/Downstream/3519;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/20226, chr12-CpG: 30/Downstream/34575
Upstream sequence
ctgcccacctcagcctcccaaagtgctgggattataggcatgagccaccacacctggccatgtacattttatctcaaGAAAAAAAAAAAgaatcactgag
Downstream sequence
gaaggtagtaagaaacagattccttagctccacccctagagattctgactccgtaggtctgaggcaaggcctcaggtacgaagatattttttaaatctcc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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