Basic Information
VIS ID
TVIS30011914
Fusion event
HIV-PSEN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
73659012/73192304 (Hg38)
End
73659012/73192304 (Hg38)
Orient
-
Location type
Intronic
Target gene
PSEN1
miRNAs that regulate target gene
hsa-mir-562 ; hsa-mir-155-5p ; hsa-mir-183-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-935 ; hsa-mir-5000-5p
Nearest miRNA
hsa-mir-208a/Upstream/675406; hsa-mir-1185-1/Downstream/566443;
Nearest TSS
ENST00000550708/Upstream/24475; ENST00000554995/Downstream/5406;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/55265, chr14-CpG: 119/Downstream/45042
Upstream sequence
agacgggtggattgcttgaacccaggagttttagaccaacctgggcaacatgttgaaaccctatctgtacaaaaaaaattagaaaaattagctgggcata
Downstream sequence
gtggcacacacctgttgtcccagctacttaggaggctgagctgggaagaccacctgatctccggaggtaaagactgcagtgagccgtgattgcaccactt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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