Basic Information
VIS ID
TVIS30011926
Fusion event
HIV-ITPK1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
93579571/93113226 (Hg38)
End
93579571/93113226 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITPK1
miRNAs that regulate target gene
hsa-mir-421 ; hsa-mir-218-5p ; hsa-mir-6744-5p ; hsa-mir-4537 ; hsa-mir-6872-3p ; hsa-mir-6746-3p
Nearest miRNA
hsa-mir-1260a/Upstream/15846936; hsa-mir-1185-1/Downstream/835000;
Nearest TSS
ENST00000550708/Upstream/45774; ENST00000283534/Downstream/2046;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/54154, chr14-CpG: 193/Downstream/1512
Upstream sequence
AGAATGGCCCTGATGACTTCTGCCTTCTTTGAAGCCAATATTTTGGCCAAAGGAAGGCAACTAGACTTTGAAGACAACAACTCTTTCAGAGAAAGTAATG
Downstream sequence
CTCTACTCCCCAGAACGTTGATAGCATAGCTTGCTCTGAACCTCCCACCCCTTTAAAGGAAGAATGTCTACAAGGTCAAGCCAATCTGCAGGTCCAGCAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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