Basic Information
VIS ID
TVIS30011974
Fusion event
HIV-MYO1E integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
59453365/59161166 (Hg38)
End
59453365/59161166 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA15A
Target gene
MYO1E
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-30b-5p ; hsa-mir-93-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-10393/Upstream/3788132; hsa-mir-11181/Downstream/10017;
Nearest TSS
ENST00000557528/Upstream/7524; ENST00000307144/Downstream/45595;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/55616, chr15-CpG: 28/Downstream/45594
Upstream sequence
ACTTACGGGAGTTCTTGGGCAGTCCAGGTCCGATGCTGACCTGCAGCACTTTGTTACTGGGCTTGAGGACAGCCAGGTCCCCAAACCCTTGGTGGAACTG
Downstream sequence
CACTTGCCGGGAGCCCCCTGCACTCCAGGGGCCCCAGTTTTCCTTTTTCAACTTCAGTTCAAGCCTGCAAAAAGCACAGTGGGGTTAACAGGTCGAAGGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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