Basic Information
VIS ID
TVIS30012074
Fusion event
HIV-MGRN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
4680998/4630997 (Hg38)
End
4680998/4630997 (Hg38)
Orient
-
Location type
Intronic
Target gene
MGRN1
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-181d-5p ; hsa-mir-210-3p ; hsa-mir-542-3p ; hsa-mir-675-3p ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-648 ; hsa-mir-4433a-3p ; hsa-mir-4658 ; hsa-mir-4722-5p ; hsa-mir-4666b ; hsa-mir-6790-5p ; hsa-mir-223-5p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-455-5p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-6840-5p ; hsa-mir-3659 ; hsa-mir-2277-3p
Nearest miRNA
hsa-mir-1225/Upstream/1145528; hsa-mir-11401/Downstream/40321;
Nearest TSS
ENST00000527434/Upstream/6036; ENST00000615397/Downstream/9626;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/5787, chr16-CpG: 62/Downstream/17221
Upstream sequence
acttcctggctcaggtgattctcccacctcagcctcccaagtagctgggttttcccagctatgtatgtgtaccactatgcccagcaaagtttttgtattt
Downstream sequence
tttttgtagagacagggtttcaccgtgttgtccaggctggcctcaaagtcctggactcaagcaatctgcccaccttggccttccagagtgctgggattac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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