Basic Information
VIS ID
TVIS30012268
Fusion event
HIV-TAF15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
34162875/35835871 (Hg38)
End
34162875/35835871 (Hg38)
Orient
-
Location type
Intronic
Target gene
TAF15
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-181a-5p ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-501-5p ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-10a-5p ; hsa-mir-196a-5p
Nearest miRNA
hsa-mir-1180/Upstream/3485669; hsa-mir-10226/Downstream/1197874;
Nearest TSS
ENST00000595228/Upstream/2347; ENST00000604694/Downstream/8206;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/25965, chr17-CpG: 21/Downstream/94771
Nearest cancer related gene
TAF15(OG, No orient, 0)
Upstream sequence
GTAAAGAATTAGAGTTCTCCAGAGAAAGAAATGCTAAACTAACTCCATCTCTTCATGACGTTTAGCCCTATGTCTGAATCTGAAGAGTGAGGTTTGTAAG
Downstream sequence
ATCATCCTTAATTGGTATATAGGTATTTCACATAGTGTGGACTTGATCCACTTTACTTGAAATTTAGTTGTAAGAATTGATCAACCAAATAATTACTGTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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