Basic Information
VIS ID
TVIS30012275
Fusion event
HIV-MED1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
37592959/39436706 (Hg38)
End
37592959/39436706 (Hg38)
Orient
-
Location type
Intronic
Target gene
MED1
miRNAs that regulate target gene
hsa-mir-205-5p ; hsa-mir-96-5p ; hsa-mir-125b-5p ; hsa-mir-10a-5p ; hsa-mir-30c-5p ; hsa-mir-137
Nearest miRNA
hsa-mir-1180/Upstream/139197; hsa-mir-10226/Downstream/289789;
Nearest TSS
ENST00000595228/Upstream/5470; ENST00000581593/Downstream/14562;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/33977, chr17-CpG: 29/Downstream/14434
Upstream sequence
TCTTCAAGCCTAGCACTTTTACTGTAACACACATGTACCTTCTAAATGAAACAATTTTTCCCAAAATCAAAGCGAAAAAGTTATTTTCATGGTATCATAC
Downstream sequence
TCAATTATCAAGCCTTCACTGATTCAATGATTACCTTCTATTTATTTTGTTCCACACATAAttctttattatttttttttttgagacagtctcactccgt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate