Basic Information
VIS ID
TVIS30012296
Fusion event
HIV-STAT5B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
40358498/42206480 (Hg38)
End
40358498/42206480 (Hg38)
Orient
+
Location type
Intronic
Target gene
STAT5B
miRNAs that regulate target gene
hsa-mir-23b-3p ; hsa-mir-1229-3p ; hsa-mir-93-3p ; hsa-mir-324-3p ; hsa-mir-134-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-335-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-526b-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4762-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-106b-3p ; hsa-mir-150-5p ; hsa-mir-28-5p ; hsa-mir-182-3p ; hsa-mir-28-3p
Nearest miRNA
hsa-mir-1180/Upstream/689263; hsa-mir-10226/Downstream/288293;
Nearest TSS
ENST00000595228/Upstream/3527; ENST00000592536/Downstream/4112;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/21889, chr17-CpG: 126/Downstream/69453
Upstream sequence
cgcccggcctgaatatgtttccttgtttatggtcttcgttctgctgctagataacctccaCACAGGAAGTTCAAGCAACGGGTGATGCAATGTATAATAC
Downstream sequence
ATATCTATATATAGAGTGCAAGAATAGTCACTAAATCATCCATAGAGGTTAATCTCTAGATGAGAGATGTTGTGTGGTATCTGtttttttgttttctttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate