Basic Information
VIS ID
TVIS30012298
Fusion event
HIV-STAT5B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
40398921/42246903 (Hg38)
End
40398921/42246903 (Hg38)
Orient
-
Location type
Intronic
Target gene
STAT5B
miRNAs that regulate target gene
hsa-mir-23b-3p ; hsa-mir-1229-3p ; hsa-mir-93-3p ; hsa-mir-324-3p ; hsa-mir-134-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-335-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-526b-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4762-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-106b-3p ; hsa-mir-150-5p ; hsa-mir-28-5p ; hsa-mir-182-3p ; hsa-mir-28-3p
Nearest miRNA
hsa-mir-1180/Upstream/729686; hsa-mir-10226/Downstream/247870;
Nearest TSS
ENST00000595228/Upstream/29032; ENST00000592536/Downstream/21684;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/62312, chr17-CpG: 126/Downstream/29030
Upstream sequence
ATCCCTTACCTCTAATCACATACCTGAACACAACTGGCTTACGTGAAGGCCGTTGACAGTTCAAGAGTAACAATTCAAGGTGTCTAGAAAGCTATCATTA
Downstream sequence
CAAGAGCAGATCACAGGAAACCTCAGCTGTTGGTTCCTAACTTCGCTCCTACTCAAAGGCCAACAGAACCGGGGAGAAATCTTCCTGTTTTGTTGATATC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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