Basic Information
VIS ID
TVIS30012377
Fusion event
HIV-PITPNC1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
65451994/67455878 (Hg38)
End
65451994/67455878 (Hg38)
Orient
-
Location type
Intronic
Target gene
PITPNC1
miRNAs that regulate target gene
hsa-mir-126-3p ; hsa-mir-335-5p ; hsa-mir-142-3p ; hsa-mir-7-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-4672 ; hsa-mir-5011-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6768-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-369-3p ; hsa-mir-548v ; hsa-mir-548d-3p ; hsa-mir-548au-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-6516-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-488-3p ; hsa-mir-657 ; hsa-mir-4635 ; hsa-mir-3665 ; hsa-mir-4678 ; hsa-mir-935 ; hsa-mir-5003-3p ; hsa-mir-140-3p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-10226/Upstream/668710; hsa-mir-1250/Downstream/15611;
Nearest TSS
ENST00000595228/Upstream/76912; ENST00000584554/Downstream/1660;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/76863, chr17-CpG: 43/Downstream/261774
Upstream sequence
aagttgtctcctaggaaagttgtatagttagtcattcccaGATGATGTATGGAGCACTGTTGTTTCAATGCCCCTCTTATATTTTTACTTGGTTACTGGG
Downstream sequence
TTTGTGAACTTAAAAAATTAAAACATTCTTATTTTAAAAACAATTCAaatatataaaacatgtacagataataatgaaacgtacacttatgtacccagca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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