Basic Information
VIS ID
TVIS30012391
Fusion event
HIV-LLGL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
73526144/75530063 (Hg38)
End
73526144/75530063 (Hg38)
Orient
+
Location type
Intronic
Target gene
LLGL2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-548d-3p ; hsa-mir-548j-3p ; hsa-mir-548h-3p ; hsa-mir-548x-3p ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-5582-3p ; hsa-mir-548bb-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4745-3p ; hsa-mir-1538 ; hsa-mir-3202 ; hsa-mir-5008-5p ; hsa-mir-1247-3p ; hsa-mir-1324 ; hsa-mir-4747-3p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-4477a
Nearest miRNA
hsa-mir-10226/Upstream/31435; hsa-mir-1250/Downstream/254458;
Nearest TSS
ENST00000595228/Upstream/4274; ENST00000580925/Downstream/2430;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/3604, chr17-CpG: 21/Downstream/28680
Upstream sequence
agtgtggtcactgacccgtgctgagctttgttttcacagatgagaagatgagaaaggtcactagcacgtgtggcctgccacacagCAGGCACCCAGTGAG
Downstream sequence
GGTGGACTCAACTTCCATGAAGCATAAGAGGCATCCGTCTGTCCCAGGCCTTTGGGTGGGCACTTGGGCCTTTTGGAAGTGCCTGATGGGTTTAGGGAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate