Basic Information
VIS ID
TVIS30012403
Fusion event
HIV-MGAT5B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
74888216/76892134 (Hg38)
End
74888216/76892134 (Hg38)
Orient
+
Location type
Intronic
Target gene
MGAT5B
miRNAs that regulate target gene
hsa-mir-6775-5p ; hsa-mir-7109-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6795-5p ; hsa-mir-6887-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-3622b-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-5681a ; hsa-mir-6805-5p ; hsa-mir-5584-5p ; hsa-mir-4793-5p ; hsa-mir-874-5p ; hsa-mir-4749-3p ; hsa-mir-324-5p ; hsa-mir-6787-3p ; hsa-mir-6887-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6849-3p
Nearest miRNA
hsa-mir-10226/Upstream/155586; hsa-mir-1250/Downstream/197283;
Nearest TSS
ENST00000595228/Upstream/19423; ENST00000563627/Downstream/31716;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9761, chr17-CpG: 20/Downstream/40494
Upstream sequence
TCAGGGCCAGGAGGTAGGAAGtctctttttgagacagggtctcactctgttgcccaacctggagtgcagtggctcgatcacggctcactgaagatctcaa
Downstream sequence
ccttctgggctcaagcaatcctcccacctcagcctccagagtagctgggaccacaggcatgtgccaccacacctggctaatttctgtatttttaggggag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate