Basic Information
VIS ID
TVIS30012468
Fusion event
HIV-EPG5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
43517071/45937105 (Hg38)
End
43517071/45937105 (Hg38)
Orient
-
Location type
Intronic
Target gene
EPG5
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-570-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-889-3p ; hsa-mir-610 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-4314 ; hsa-mir-7977 ; hsa-mir-3178 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6089 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-383-3p ; hsa-mir-514a-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p
Nearest miRNA
hsa-mir-1-2/Upstream/966939; hsa-mir-122/Downstream/1443391;
Nearest TSS
ENST00000575820/Upstream/19409; ENST00000591098/Downstream/30169;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/97967, chr18-CpG: 45/Downstream/30122
Upstream sequence
CTGAACAAGAGATTAAGAAACTTCTCTAAGGTCAGTTGGGCCAGGTTTCTATCTTATTAGTTAATTATCCTAACACTTCACATGGGACCTGATGCTGTTT
Downstream sequence
TATACCCCAAAACAAAGAAGGGAAATTGTAGAGGACTTAAAAGTAATATCACAAACAGGGTGTATTTCAGGCTATAAAATTCCCTATATGGCAGACATTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate