Basic Information
VIS ID
TVIS30012471
Fusion event
HIV-ACAA2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
47337556/49811186 (Hg38)
End
47337556/49811186 (Hg38)
Orient
+
Location type
Intronic
Target gene
ACAA2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-186-5p ; hsa-mir-6776-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6844 ; hsa-mir-7977 ; hsa-mir-143-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6499-3p ; hsa-mir-9-5p ; hsa-mir-5693 ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1-2/Upstream/323764; hsa-mir-122/Downstream/315313;
Nearest TSS
ENST00000575820/Upstream/24567; ENST00000615535/Downstream/345;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/249028, chr18-CpG: 60/Downstream/1855
Upstream sequence
TCTCATTTGAACACCCTGAAAATTCAGAGGCTAAAAATTTCCCAAAACTGAAAGACAGTGAAGAGACCTATTAACCCAGAGTGTAGTGAGTCCAAGTAGC
Downstream sequence
TCCAAGAAAGGCCCTGGAAAGATGTGCTGAGTTGACAATACAGGAAAAGCACCACTAGGAAAGAAACAGGAGCACTACCTTTCTATCACATTGTTAGGTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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