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Viral Integration Site DataBase
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TVIS30012498
Basic Information
VIS ID
TVIS30012498
Fusion event
HIV-DOT1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2206368/2206369 (Hg38)
End
2206368/2206369 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
DOT1L
miRNAs that regulate target gene
hsa-mir-92a-3p
;
hsa-let-7c-5p
;
hsa-mir-412-3p
;
hsa-mir-541-5p
;
hsa-mir-485-5p
;
hsa-mir-1203
;
hsa-mir-1208
;
hsa-mir-1227-5p
;
hsa-mir-1249-5p
;
hsa-mir-128-1-5p
;
hsa-mir-128-2-5p
;
hsa-mir-2113
;
hsa-mir-29a-3p
;
hsa-mir-29b-3p
;
hsa-mir-29c-3p
;
hsa-mir-329-5p
;
hsa-mir-3663-3p
;
hsa-mir-4443
;
hsa-mir-4447
;
hsa-mir-4472
;
hsa-mir-452-5p
;
hsa-mir-4676-3p
;
hsa-mir-4781-3p
;
hsa-mir-5010-3p
;
hsa-mir-512-5p
;
hsa-mir-5585-3p
;
hsa-mir-5690
;
hsa-mir-5692a
;
hsa-mir-589-3p
;
hsa-mir-6515-5p
;
hsa-mir-6751-5p
;
hsa-mir-6752-5p
;
hsa-mir-6756-5p
;
hsa-mir-6762-5p
;
hsa-mir-6766-5p
;
hsa-mir-6787-3p
;
hsa-mir-6797-5p
;
hsa-mir-6803-5p
;
hsa-mir-6804-5p
;
hsa-mir-6835-5p
;
hsa-mir-6842-5p
;
hsa-mir-6845-5p
;
hsa-mir-7110-5p
;
hsa-mir-767-5p
;
hsa-mir-892c-3p
;
hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-1302-11/Upstream/390131; hsa-let-7e/Downstream/27693;
Nearest TSS
ENST00000633603/Upstream/41901;
ENST00000591498/Downstream/5868;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/5014
,
chr19-CpG: 23/Downstream/7492
Upstream sequence
gccactgcaccGCGCCGAGAATGTTTTTTAAAGAAGCATTATTTGtaggaggttgggcgtggtggctcacttgaggccaggagttccagacaagcctggc
Downstream sequence
cagcagggtgaaacccgctctctactaaaaatccaaaaattagccaggtgtggtggtgtgcgcctgtaatcacagctactcgcaaggctgaggcaggaga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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