Basic Information
VIS ID
TVIS30012510
Fusion event
HIV-VAV1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
6836627/6836616 (Hg38)
End
6836627/6836616 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
VAV1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1227/Upstream/99838; hsa-let-7e/Downstream/780823;
Nearest TSS
ENST00000633603/Upstream/807; ENST00000596944/Downstream/50950;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/68467, chr19-CpG: 25/Downstream/238125
Nearest cancer related gene
VAV1(OG, No orient, 0)
Upstream sequence
TGGAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAGGTACAGGCTGGGGCCACAAGAGTGATGGGGTGGGACCCAAGTGTAGGG
Downstream sequence
TTATGGATTCATGTGGTCTCAGGGAGTTGGGTCATAGTTCCACCATGCTCTGGAGGTGATGCCTGGGGAGTGGGGTAGGTAGACTGAGACTTCTGGGCAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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