Basic Information
VIS ID
TVIS30012528
Fusion event
HIV-ICAM1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10393697/10283021 (Hg38)
End
10393697/10283021 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ICAM1
miRNAs that regulate target gene
hsa-mir-17-3p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-31-5p ; hsa-mir-17-5p ; hsa-mir-155-5p ; hsa-mir-1256 ; hsa-mir-21-5p ; hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-296-3p ; hsa-mir-146a-5p ; hsa-mir-485-5p ; hsa-mir-6884-5p ; hsa-mir-93-5p ; hsa-mir-324-3p ; hsa-mir-3941 ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-3188 ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-3186-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-141-5p
Nearest miRNA
hsa-mir-1227/Upstream/52536; hsa-let-7e/Downstream/120437;
Nearest TSS
ENST00000633603/Upstream/763; ENST00000592686/Downstream/261;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/11732, chr19-CpG: 80/Downstream/3906
Upstream sequence
agaattgcttgaacccaggaggcagaggttgcagtgagccaagatcatgccatcaccctccagcctgggcgacagaaggagactcagtctaaaaacttaa
Downstream sequence
ttaattaattaattaaaaataaaaatacaaaaattaacctggtgtggtggtgtgtgcctgtaatctaagctactcaggaggctgaggcaggagaatcccc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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