Basic Information
VIS ID
TVIS30012530
Fusion event
HIV-ZNF69 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
12015107/11904292 (Hg38)
End
12015107/11904292 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ZNF69
miRNAs that regulate target gene
hsa-mir-4443 ; hsa-mir-1273e ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-5192 ; hsa-mir-4722-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-4308 ; hsa-mir-4254 ; hsa-mir-4768-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6165 ; hsa-mir-504-5p ; hsa-mir-6732-3p
Nearest miRNA
hsa-mir-1181/Upstream/408670; hsa-let-7e/Downstream/799309;
Nearest TSS
ENST00000633603/Upstream/16437; ENST00000254321/Downstream/20776;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/15976, chr19-CpG: 48/Downstream/20792
Upstream sequence
gaacagcctgggcaacataacgagaccacatatcaacaacagcaaaaaattagctgggcattgtggtctgtagtcccagctactcaggaggctgaggcag
Downstream sequence
gaggatcacttgagccagtaaaggctgcagtaagctatgatgatatcactgcactccagtgtgggcaacaggacgagacccctaaataaaagaaaaaTGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate