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VISDB
Viral Integration Site DataBase
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TVIS30012544
Basic Information
VIS ID
TVIS30012544
Fusion event
HIV-BRD4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
15429484/15318673 (Hg38)
End
15429484/15318673 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
BRD4
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-2110
;
hsa-mir-877-3p
;
hsa-mir-455-3p
;
hsa-mir-484
;
hsa-mir-320a
;
hsa-mir-544a
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-450b-5p
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-623
;
hsa-mir-6731-3p
;
hsa-mir-6832-3p
;
hsa-mir-3938
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-3613-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-380-3p
;
hsa-mir-411-3p
;
hsa-mir-379-3p
;
hsa-mir-4495
;
hsa-mir-1228-3p
;
hsa-mir-8485
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-1306-5p
Nearest miRNA
hsa-mir-10395/Upstream/139323; hsa-let-7e/Downstream/130875;
Nearest TSS
ENST00000633603/Upstream/38222;
ENST00000601005/Downstream/13233;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/79495
,
chr19-CpG: 154/Downstream/12777
Nearby gene
AKAP8
(No orient, 34848)
Nearest cancer related gene
BRD4
(OG, No orient, 0)
Upstream sequence
ATGCGTAAGCAAATGTCCCGCAGCACAGGGCACACATTAAGCCACGTAAGGGACCACAGCATAAATCTTGTAAGCCTACCCACATCCAACACTACCACAT
Downstream sequence
AAATAATGAGGCTGGCTAGGAACCATTCAGTTACCTTCTGGAGCAAAGGCTCCATACCAACAGCAAATCATGGAGACAGTTTACAAACAGCAGCAGCTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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