Basic Information
VIS ID
TVIS30012550
Fusion event
HIV-EPS15L1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
16470506/16359695 (Hg38)
End
16470506/16359695 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
EPS15L1
miRNAs that regulate target gene
hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-885-3p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-6804-5p ; hsa-mir-185-5p ; hsa-mir-558 ; hsa-mir-1233-3p ; hsa-mir-3192-5p ; hsa-mir-5739 ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-6779-3p ; hsa-mir-3678-3p ; hsa-mir-2467-3p ; hsa-mir-6801-5p ; hsa-mir-4257 ; hsa-mir-759 ; hsa-mir-329-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4803 ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p
Nearest miRNA
hsa-mir-10395/Upstream/910087; hsa-let-7e/Downstream/1922382;
Nearest TSS
ENST00000633603/Upstream/6513; ENST00000587343/Downstream/2258;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3869, chr19-CpG: 22/Downstream/58252
Upstream sequence
catgcctgtaatcccaacactttgggagcctgaggcagaaggatcatttgagcccagagttcaaagaccagactgggtagtaaagtgagaccttgtctct
Downstream sequence
atcagaacattttaaaattagccagatgtggtggtgcgcgcctgaggtcccagctacgtgggaggctgaggtgggacgattgcttgagcccaggaggtca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate