Basic Information
VIS ID
TVIS30012577
Fusion event
HIV-ZNF181 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
35230973/34740068 (Hg38)
End
35230973/34740068 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF181
miRNAs that regulate target gene
hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-98-3p ; hsa-mir-580-5p ; hsa-mir-3662 ; hsa-mir-4698 ; hsa-mir-8070 ; hsa-mir-758-3p ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300
Nearest miRNA
hsa-mir-10395/Upstream/14340714; hsa-let-7e/Downstream/382632;
Nearest TSS
ENST00000633603/Upstream/5119; ENST00000600348/Downstream/33132;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5657, chr19-CpG: 60/Downstream/32675
Upstream sequence
ATGGGAAATCACTTTTCTAAAGCTGAGCGTTGTAGATGAAATATGAACATATTAGAGGAAAAAATGAACATATATAAATATGTTTCTAGGAATATTTTCT
Downstream sequence
AATGTCCAATAAATGACATGATTCACACAGTTTCTTCATAACTTCAGAAAGCCTAAATCTTTGTCAGCTATAAAGAGCATTTAGATTATTGTGTTTTTAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate