Basic Information
VIS ID
TVIS30012580
Fusion event
HIV-PROSER3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
36253052/35762151 (Hg38)
End
36253052/35762151 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
PROSER3
miRNAs that regulate target gene
hsa-mir-331-3p ; hsa-mir-196a-5p ; hsa-mir-1202 ; hsa-mir-128-3p ; hsa-mir-185-3p ; hsa-mir-216a-3p ; hsa-mir-221-5p ; hsa-mir-3150a-5p ; hsa-mir-3150b-5p ; hsa-mir-3613-3p ; hsa-mir-3614-3p ; hsa-mir-3681-3p ; hsa-mir-3972 ; hsa-mir-4258 ; hsa-mir-4283 ; hsa-mir-4297 ; hsa-mir-4438 ; hsa-mir-4489 ; hsa-mir-4684-5p ; hsa-mir-4707-3p ; hsa-mir-4731-5p ; hsa-mir-4755-3p ; hsa-mir-4793-5p ; hsa-mir-4794 ; hsa-mir-5006-5p ; hsa-mir-5095 ; hsa-mir-548c-3p ; hsa-mir-548v ; hsa-mir-5581-5p ; hsa-mir-6502-3p ; hsa-mir-664a-5p ; hsa-mir-6789-3p ; hsa-mir-7151-3p ; hsa-mir-8073
Nearest miRNA
hsa-mir-10395/Upstream/416524; hsa-let-7e/Downstream/3647472;
Nearest TSS
ENST00000633603/Upstream/2266; ENST00000542591/Downstream/2951;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3745, chr19-CpG: 58/Downstream/13181
Upstream sequence
CAGTCGAGAGGAGCGCCAGCCTGCAGGCCCAACCCCAGCTGACTTTTGGTGGCTGCAGTCTGACTCTCCAGACCCCAGCAGTCAAAGTGCAGCAGGTACC
Downstream sequence
TCTTTCAGTGCCATCCACTACTCCCACCCCTAAACCTTTGCTGATCAATGCCCCCAGCAGCCACTCCTCCTGGCCCTCATACCTCAACTGGGGCTTCTCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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