Basic Information
VIS ID
TVIS30012583
Fusion event
HIV-ZNF875 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
37820797/37329895 (Hg38)
End
37820797/37329895 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF875
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-4674 ; hsa-mir-3115 ; hsa-mir-6824-5p ; hsa-mir-193a-5p ; hsa-mir-4437 ; hsa-mir-6783-5p ; hsa-mir-24-3p
Nearest miRNA
hsa-mir-10395/Upstream/1984268; hsa-let-7e/Downstream/2079728;
Nearest TSS
ENST00000633603/Upstream/11856; ENST00000590386/Downstream/4729;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/11764, chr19-CpG: 45/Downstream/4304
Nearby gene
ZNF875(No orient, 4783)
Upstream sequence
GGCCTTCTGGGAGGTTCCAGCTTTTCCTGGATGCTCTCTCTCTCTGGCCAGCTCAGGCTGGAGCAGTGGGTGTTGGTGCCATCCTGTGGCTATAGGTGAT
Downstream sequence
AAACCAGGTTGTGTTTTGACCCCTAGTCTTGAATCCTGGAGTTCTCACATGCGTGGATTTAAATGCTGTGTCTTTCTAAGGGCAGATTGTGCCCATTTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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