Basic Information
VIS ID
TVIS30012612
Fusion event
HIV-PPP1R37 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
45613733/45110475 (Hg38)
End
45613733/45110475 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
PPP1R37
miRNAs that regulate target gene
hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-345-3p ; hsa-mir-92b-3p ; hsa-mir-670-5p ; hsa-mir-4319 ; hsa-mir-4325 ; hsa-mir-4732-3p ; hsa-mir-6736-3p ; hsa-mir-7106-3p ; hsa-mir-7113-3p ; hsa-mir-7703 ; hsa-mir-4323 ; hsa-mir-4797-5p ; hsa-mir-6796-3p ; hsa-mir-4267 ; hsa-mir-500a-3p ; hsa-mir-580-3p ; hsa-mir-539-5p ; hsa-mir-137
Nearest miRNA
hsa-mir-10395/Upstream/351754; hsa-let-7e/Downstream/326179;
Nearest TSS
ENST00000633603/Upstream/10411; ENST00000545910/Downstream/26502;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16862, chr19-CpG: 73/Downstream/34224
Upstream sequence
agagtgctgggattacagccatgagccattgcacctggccACATTTcttacttttactcatcttttaggtctcagtcgaaatgttcttttctcttatggg
Downstream sequence
tcttttctaactattcctccaaatctgaatttgtatcccctgtgttttcccctataatatgcattttcttcttataactggtaaatttttgggtgatttg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate