Basic Information
VIS ID
TVIS30012694
Fusion event
HIV-XPO1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
GRCh37/hg19
Start
61720787/61493652 (Hg38)
End
61720787/61493652 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
XPO1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-155-5p ; hsa-mir-192-5p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-1236-3p ; hsa-mir-125a-5p ; hsa-mir-23b-3p ; hsa-mir-92a-3p ; hsa-mir-17-3p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-382-5p ; hsa-mir-485-5p ; hsa-mir-4495 ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-224-5p
Nearest miRNA
hsa-mir-1301/Upstream/1106207; hsa-mir-10b/Downstream/712174;
Nearest TSS
ENST00000437798/Upstream/658; ENST00000425779/Downstream/1091;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/21987, chr2-CpG: 64/Downstream/44619
Upstream sequence
ATAATTATTTAAGTGTGTTTTAATGTGATTTTTTTAACCAACTTCTGTTACAGGagtttcctgtgtctcattcctagactctggtttagtagattggcag
Downstream sequence
gtggccaatgaatttgcctaacgaaatcacaaccaatgttgatactgagagaaggaccacactcttgagaatcaAGGTTCTAGACTCAACTCCTTTCATG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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