Basic Information
VIS ID
TVIS30012747
Fusion event
HIV-ARHGAP15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
144071437/143313868 (Hg38)
End
144071437/143313868 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
ARHGAP15
miRNAs that regulate target gene
hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-6807-5p ; hsa-mir-4698 ; hsa-mir-586 ; hsa-mir-5700 ; hsa-mir-3662 ; hsa-mir-4764-3p ; hsa-mir-3134 ; hsa-mir-4495 ; hsa-mir-1246 ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-8087 ; hsa-mir-6750-3p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-128-1/Upstream/2727183; hsa-mir-10b/Downstream/6016410;
Nearest TSS
ENST00000437798/Upstream/66578; ENST00000548800/Downstream/121396;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1182884, chr2-CpG: 111/Downstream/622895
Upstream sequence
GTAGCCACATTGTCGTTTCTTTAATTAACCTTGATATCCTAGTACCCAGATAGCAGAGTTCATCAAGCAGGCACTTGGAACTTTTAACATTCATGCTGTT
Downstream sequence
GTACTTTGATTTTTAAGAGTTATTGTACAAAGTATATTTTTAAAATGCATTTTTATTCTGCGAGACTTAAGGTGGATGAGGAGAGGGCTTTTTTTTTTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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