Basic Information
VIS ID
TVIS30012748
Fusion event
HIV-ARHGAP15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
144322740/143565171 (Hg38)
End
144322740/143565171 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
ARHGAP15
miRNAs that regulate target gene
hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-6807-5p ; hsa-mir-4698 ; hsa-mir-586 ; hsa-mir-5700 ; hsa-mir-3662 ; hsa-mir-4764-3p ; hsa-mir-3134 ; hsa-mir-4495 ; hsa-mir-1246 ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-8087 ; hsa-mir-6750-3p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-128-1/Upstream/2978486; hsa-mir-10b/Downstream/5765107;
Nearest TSS
ENST00000437798/Upstream/8763; ENST00000549060/Downstream/6934;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1434187, chr2-CpG: 111/Downstream/371592
Upstream sequence
catacttaagaaaaattaaataactcttaggccacaaaattaatacagtattgaaggcaggaggtgaatctattttaaacttactcccaaAAATATATTG
Downstream sequence
CCTGGTAGCTGGATTCAATTTACCATGGGGAAGGGGGCAGAGAGATGTTATCTTCTTTTTAACATTAAGGAATCCCAAATCACTTATTCTCATTATAGTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate