Basic Information
VIS ID
TVIS30012751
Fusion event
HIV-MBD5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
149067003/148309434 (Hg38)
End
149067003/148309434 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2K
Target gene
MBD5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-7151-5p ; hsa-mir-6796-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-3201 ; hsa-mir-429 ; hsa-mir-4314 ; hsa-mir-4502 ; hsa-mir-4738-3p ; hsa-mir-4790-3p ; hsa-mir-4791 ; hsa-mir-6776-5p ; hsa-mir-6861-5p ; hsa-mir-8084
Nearest miRNA
hsa-mir-128-1/Upstream/7722749; hsa-mir-10b/Downstream/1020844;
Nearest TSS
ENST00000437798/Upstream/76086; ENST00000636371/Downstream/21072;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/288473, chr2-CpG: 193/Downstream/334668
Upstream sequence
agtggtttgtaattctccctgaagaggtccttcacgtcccttgtaagttgtattcctaggtattttattctctttgtagcaactgtgaatgagagttcac
Downstream sequence
tcatgattaggctgtctgtctgttactggtgtatagggtgatttttgcatgttgactttgtatcctgacactttgctgaagttgcttatcagcttaagga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate